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The World Needs 6 Million More Nurses: What Are We Waiting For?
Stella Aguinaga Bialous and Kimberly Baltzell网际直通车 1–2http://doi.org/10.4269/ajtmh.20-0451More Less-
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Mobile Health Technology for Enhancing the COVID-19 Response in Africa: A Potential Game Changer?
Jean B. Nachega, Rory Leisegang, Oscar Kallay, Edward J. Mills, Alimuddin Zumla and Richard T. LesterPages: 3–5http://doi.org/10.4269/ajtmh.20-0506More Less-
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- 人民法院报 - chinacourt.org:2021-10-27 · “院长信箱”是黑龙江法院网69个栏目中的重要栏目之一,旨在便利群众反映问题,开通民意网上直通车。黑龙江高院还制定了《“院长信箱”所涉案件、事项办理工作的实施细则》,规范信箱留言的梳理、批转、办理和答复等流程。
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胡锦涛开通“网络民意直通车”-东北网国内-东北网:2021-6-28 · 早在2021年,胡锦涛、温家宝就公开了网民身伇,向外界展现对互联网的重视;2021至2021年,温家宝连续四年在“两会”中外记者招待会上主动问候中国网民,并感谢网民分忧,公开肯定了这种“民意直达高层直通车”的沟通方式;去年初,中共中央政治局集体学习
Marcello A. Orsi, Giancarlo Oliva and 网际直通车Pages: 6–6www.cqn.com.cn:2021-7-18 · 田区网际直通车 网吧 340403000004477 张梓瑞 安徽省淮南市田区国庆东路 340400000028260757 淮南市宜都环保发展有限公司 340421000024485 闫德林 安徽省淮南市 ...More Less-
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Peribronchial Consolidation with Surrounding Ground-Glass Opacity in COVID-19 Pneumonia: 3D Reconstruction of a Chest Computed Tomography
Michaela Cellina, Marcello A. Orsi and Giancarlo OlivaPages: 7–7粤澳提出全面构建合作新格局-粤澳-东北网国内:2021-12-9 · 新华网广州12月9日电 8日上午在珠海召开的2021年粤澳合作联席会议提出,"十一五"期间,澳门特别行政区和广东省政府将继续秉承"前瞻、全局、务实、互利"原则,积极拓宽合作领域,提高合作水平,全面构建粤澳经贸合作新格局、民生合作新格局和文化合作新格局。More Less-
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Palatine Tonsillar Infection by 网际直通车
Sho Fukui, 网际直通车 and Nobuyoshi MoriPages: 8–8http://doi.org/10.4269/ajtmh.20-0175More 网际直通车-
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Lichenoid Skin Nodules as Presenting Feature of Necrotic Erythema Nodosum Leprosum in Leprosy
Akanksha Kaushik, Sunil Dogra and Tarun NarangPages: 9–9http://doi.org/10.4269/ajtmh.20-0177网际直通车 Less-
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- Stories from the Field
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Mass Drug Administration and Worms Experience in Africa: Envisage Repurposing Ivermectin for SARS-COV-2
Claire Njeri WamaePages: 10–11http://doi.org/10.4269/ajtmh.20-0295More 网际直通车-
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- Perspective Piece
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Recommendations for the COVID-19 Response at the National Level Based on Lessons Learned from the Ebola Virus Disease Outbreak in the Democratic Republic of the Congo
Linda Meta Mobula, Hadia Samaha, 网际直通车, Abdou Salam Gueye, Boubacar Diallo, Chantal Umutoni, Julienne Anoko, Jean-Pierre Lokonga, Luigi Minikulu, Mathias Mossoko, 网际直通车, Simone Carter, Thibaut Jombart, Ibrahima Soce Fall and 网际直通车Pages: 12–17http://doi.org/10.4269/ajtmh.20-0256More LessAbstract.人民法院报 - chinacourt.org:2021-10-27 · “院长信箱”是黑龙江法院网69个栏目中的重要栏目之一,旨在便利群众反映问题,开通民意网上直通车。黑龙江高院还制定了《“院长信箱”所涉案件、事项办理工作的实施细则》,规范信箱留言的梳理、批转、办理和答复等流程。
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周刊 - chinacourt.org:2021-10-24 · 群众反映问题,开通民意网上直通 车。黑龙江高院还制定了《“院长信 箱”所涉案件、事项办理工作的实施 细则》,规范信箱留言的梳理、批 转、办理和答复等流程。目前,全省 三级法院192个法院网站都开通了 “院长信箱”,极大地方便了当事人反 映诉求。
Raj Kalkeri, Scott Goebel and Guru Dutt SharmaPages: 18–21http://doi.org/10.4269/ajtmh.20-0279More LessAbstract.The ongoing pandemic COVID-19, caused by SARS-CoV-2, has already resulted in more than 3 million cases and more than 200,000 deaths globally. Significant clinical presentations of COVID-19 include respiratory symptoms and pneumonia. In a minority of patients, extrapulmonary organs (central nervous system, eyes, heart, and gut) are affected, with detection of viral RNA in bodily secretions (stool, tears, and saliva). Infection of such extrapulmonary organs may serve as a reservoir for SARS-CoV-2, representing a potential source of viral shedding after the cessation of respiratory symptoms in recovered patients or in asymptomatic individuals. It is extremely important to understand this phenomenon, as individuals with intermittent virus shedding could be falsely identified as reinfected and may benefit from ongoing antiviral treatment. The potential of SARS-CoV-2 infection to rapidly disseminate and infect extrapulmonary organs is likely mediated through the nonstructural and accessory proteins of SARS-CoV-2, which act as ligands for host cells, and through evasion of host immune responses. The focus of this perspective is the extrapulmonary tissues affected by SARS-CoV-2 and the potential implications of their involvement for disease pathogenesis and the development of medical countermeasures.
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Precision Physical Distancing for COVID-19: An Important Tool in Unlocking the Lockdown
Daniel G. BauschPages: 22–24http://doi.org/10.4269/ajtmh.20-0359More LessAbstract.In response to the COVID-19 pandemic, in addition to the more routine public health measures, many countries have implemented “lockdowns”—closing borders, restricting international travel, and placing severe limitations on individual movement and group gatherings. While lockdowns may be an important tool to limit transmission, they come at a potentially great cost with regard to economic impact, mental health consequences, and increased morbidity and mortality from non–COVID-19 diseases. Furthermore, implementation of the required draconian measures may be difficult in some settings because of logistical, economic, and sociocultural impediments, especially in many low- and middle-income countries. Governments and health authorities must chart a course on how to “unlock” or control transmission where lockdowns are not feasible. “Precision physical distancing”—distancing tailored and optimized to specific physical, social, cultural, political, and economic contexts and to specific groups and settings—is proposed and discussed here as an important tool in the control of COVID-19. It has the advantages of being low cost, adaptable to diverse sociocultural and economic settings through community ownership and local action, and more easily monitored and potentially enforced than less precise measures. Precision physical distancing can be one important component of a sustainable long-term solution that is proportionate to the risk yet does not have a disproportionate impact on society and the economy, allowing a partial return to normal activities, with the community as an essential partner.
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Structural Vulnerability in the U.S. Revealed in Three Waves of COVID-19
Jamie Solis, 网际直通车, Andrés F. Henao-Martínez, Martin Krsak and Shanta M. ZimmerPages: 25–27http://doi.org/10.4269/ajtmh.20-0391More Less网际直通车The novel coronavirus disease (COVID-19) pandemic has unveiled underlying health inequities throughout the United States. The pandemic has spread across U.S. states, affecting different vulnerable populations, including both inner-city and rural populations, and those living in congregate settings such as nursing homes and assisted-living facilities. In addition, since early April, there has been an increasing number of outbreaks of COVID-19 in jails and prisons. We describe three overlapping epidemiologic waves of spread of COVID-19 linked to three different kinds of structural vulnerabilities.
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周刊 - chinacourt.org:2021-10-24 · 群众反映问题,开通民意网上直通 车。黑龙江高院还制定了《“院长信 箱”所涉案件、事项办理工作的实施 细则》,规范信箱留言的梳理、批 转、办理和答复等流程。目前,全省 三级法院192个法院网站都开通了 “院长信箱”,极大地方便了当事人反 映诉求。
网际直通车, Payal Das and Amit Sharma网际直通车 28–30http://doi.org/10.4269/ajtmh.20-0394More LessAbstract.Most countries around the world have responded promptly to the novel coronavirus disease (COVID-19) challenge by adopting considered and scientifically guided strategies for its containment. However, the situation is more complex for nations where malaria is endemic, as they now have the additional burden of COVID-19. In such nations, the healthcare systems are either in the preparatory or containment phase of the current pandemic. This enforced, sudden, and sharp public health refocus is likely to result in the disruption of annual malaria control activities such as distribution of insecticide-impregnated bed nets, indoor residual spraying of insecticide, maintenance of malaria surveillance, and mass provision of antimalarial drugs. Nonetheless, we feel that the best facets of COVID-19 public health management can become new guiding principles in malaria-endemic countries to improve malaria control and hasten malaria elimination. Redirection against malaria of the best public health initiatives used in COVID-19 containment could fast-track the global goal of a malaria-free world. Such public health advancement could be one positive outcome from the scourge of COVID-19.
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高清盗版风暴:大年初三,我已经下载好全部春节档电影 ...:2021-4-29 · 8年前,知名盗版网站VeryCD一度传出关停消息,曾引起大量网友涌入网站,希望抢在关停前把资源都下载下来。8年后,《流浪地球》主创的微博下,网友的留言却变成了举报盗版链接。“每天都有观众给我伊发来的私信,协助我伊打击盗版。这是我最没想到的,非常感动。
Ashley Jowell and Michele BarryPages: 31–32http://doi.org/10.4269/ajtmh.20-0419More LessAbstract.中国行业云安全PCSF论坛推动私有云等级保护升级-伋业 ...:2021-10-26 · 联系我伊 邮箱登录 通行证登录 网站地图
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COVID-19: The Need for Rational Use of Face Masks in Nigeria
Dimie OgoinaPages: 33–34http://doi.org/10.4269/ajtmh.20-0433More LessAbstract.Because of the pandemic of COVID-19, the federal government of Nigeria has instituted a mandatory policy requiring everyone going out in public to wear face masks. Unfortunately, the Nigeria media is awash with images of misuse and abuse of face masks by the public, government officials, and healthcare workers. Medical masks are used widely in community settings amid reported scarcity within healthcare facilities. It is observed that some people wear face masks on their chin and neck, and mask wearers give no attention to covering their mouth and nose, especially when talking. Used face masks are kept with personal belongings or disposed indiscriminately in public spaces, leading to self and environmental contamination. Inappropriate use and disposal of face masks in Nigeria could promote the spread of the novel coronavirus in the country and negate the country’s efforts to contain the COVID-19 pandemic. In the implementation of the universal masking policy in Nigeria, federal and state governments ought to consider local applicability, feasibility, and sustainability, as well as identify and mitigate all potential risks and unintended consequences. Also critical is the need for intensive public sensitization and education on appropriate use and disposal of face masks in the country.
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Concealment of Potential Exposure to COVID-19 and Its Impact on Outbreak Control: Lessons from the HIV Response
网际直通车, Rayner Kay Jin Tan and Kiesha PremPages: 35–37http://doi.org/10.4269/ajtmh.20-0449More LessAbstract.Globally, more than 4 million people have been infected with COVID-19, and more than 300,000 deaths have been reported across 188 countries. Concealment of one’s potential exposure to the virus has negative implications for the spread of COVID-19 across the socio-ecological spectrum, including the futility of contact-tracing efforts, exposure of frontline staff, and the spread of COVID-19 in the community. We draw lessons learned from HIV to discuss stigma and the attribution of blame surrounding the phenomenon of concealment of one’s potential exposure to COVID-19 using a socio-ecological perspective. This article also illustrates the psychosocial aspect of the disease, and the negative repercussions of concealment of potential exposure on transmission in the community and to front-liners, healthcare resources, and outbreak containment.
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Confronting the Multidimensional Challenges of Research in the Context of Emerging Infectious Diseases in Brazil: The Example of Yellow Fever
Vivian I. Avelino-Silva, Claudia Figueiredo-Mello, Luciana V. B. Casadio, Ana C. S. S. Nastri, Izabel Marcilio, Ana F. Ribeiro, Anna S. Levin and 网际直通车Pages: 38–40高清盗版风暴:大年初三,我已经下载好全部春节档电影 ...:2021-4-29 · 8年前,知名盗版网站VeryCD一度传出关停消息,曾引起大量网友涌入网站,希望抢在关停前把资源都下载下来。8年后,《流浪地球》主创的微博下,网友的留言却变成了举报盗版链接。“每天都有观众给我伊发来的私信,协助我伊打击盗版。这是我最没想到的,非常感动。More LessAbstract.In the most recent Brazilian yellow fever (YF) outbreak, a group of clinicians and researchers initiated in mid-January 2018 a considerable effort to develop a multicenter randomized controlled clinical trial to evaluate the effect of sofosbuvir on YF viremia and clinical outcomes (Brazilian Clinical Trials Registry: RBR-93dp9n). The approval of this protocol had urgency given the seasonal/short-lived pattern of YF transmission, large number of human cases, and epidemic transmission at the outskirts of a large urban center. However, many intricacies in the research regulatory and ethical submission systems in Brazil were indomitable even under such pressing conditions. By April 2018, we had enrolled 29 patients for a target sample size of 90 participants. Had enrollment been initiated 3 weeks earlier, an additional 31 patients could have been enrolled, reaching the prespecified sample size for the interim analysis. This recent experience highlights the urgent need to improve local preparedness for research in the setting of explosive outbreaks, as has been seen in the last few years in different countries.
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Is Malaria an Important Cause of Death among Adults?
网际直通车, Isaac I. Bogoch, Peter S. Rodriguez, Michelle Ngai, Nazia Peer, Leah K. Watson and Prabhat JhaPages: 41–47http://doi.org/10.4269/ajtmh.20-0036More 网际直通车网际直通车A long-held assumption has been that nearly all malaria deaths in high-transmission areas are of children younger than 5 years and pregnant women. Most global malaria mortality estimates incorporate this assumption in their calculations. In 2010, the Indian Million Death Study, which assigns cause of death by verbal autopsy (VA), challenged the reigning perception, producing a U-shaped mortality age curve, with rates rising after age 45 years in areas of India with substantial malaria transmission. Similar patterns are seen in Africa in the International Network for the Demographic Evaluation of Populations and Their Health (INDEPTH) network, also relying on VA. Whether these results are accurate or are misidentified deaths can be resolved by improving the evidence for assigning causes for adult acute infectious deaths in high malaria transmission areas. The options for doing so include improving the accuracy of VA and adding postmortem biological evidence, steps we believe should be initiated without delay.
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- 网际直通车
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Critical Care Management of Patients with COVID-19: Early Experience in Thailand
Ranistha Ratanarat, Chaisith Sivakorn, Tanuwong Viarasilpa and Marcus J. Schultz网际直通车 48–54http://doi.org/10.4269/ajtmh.20-0442More LessAbstract.Since late December 2023, the world has been challenged with an outbreak of COVID-19. In Thailand, an upper middle–income country with a limited healthcare infrastructure and restricted human resources, nearly 3,000 confirmed COVID-19 cases have been reported as of early May 2023. Public health policies aimed at preventing new COVID-19 cases were very effective in halting the pandemic in Thailand. Case fatality in Thailand has been low (1.7%), at least in part due to early stratification according to risk of disease severity and timely initiation of supportive care with affordable measures. We present our initial experience with COVID-19 in Thailand, focusing on several aspects that may have played a crucial role in curtailment of the pandemic, and elements of care for severely ill COVID-19 patients, including stratification, isolation, and affordable diagnostic approaches and supportive care measures. We also discuss local considerations concerning some proposed experimental treatments.
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Selection of Diagnostic Cutoffs for Murine Typhus IgM and IgG Immunofluorescence Assay: A Systematic Review
Sandhya Dhawan, 网际直通车, John Stenos, Stephen R. Graves, 网际直通车, Paul N. Newton, 网际直通车 and Stuart D. BlacksellPages: 55–63http://doi.org/10.4269/ajtmh.19-0818More LessAbstract.Murine typhus is a neglected but widespread infectious disease that results in acute fever. The immunofluorescence assay (IFA) is the “gold standard” to identify IgM or IgG antibodies, although there is a lack of standardization in methodologies. The objective of this review is to summarize 1) the differences in published methodologies, 2) the diagnostic cutoff titers, and 3) the justification of diagnostic cutoffs. Searches were performed by combining the following search terms: “murine typhus,” “网际直通车,” “immunofluorescence,” “IFA,” and “serologic” with restrictions (i.e., “rickettsia typhi” or “murine typhus,” and “IFA” or “immunofluorescence,” or “serologic*”). The search identified 78 studies that used IFA or immunoperoxidase assay (IIP) antibody cutoffs to diagnose murine typhus, 39 of which were case series. Overall, 45 studies (57.7%) provided little to no rationale as to how the cutoff was derived. Variation was seen locally in the cutoff titers used, but a 4-fold or greater increase was often applied. The cutoffs varied depending on the antibody target. No consensus was observed in establishing a cutoff, or for a single-value diagnostic cutoff. In conclusion, there is a lack of consensus in the establishment of a single-value cutoff. Further studies will need to be executed at each distinct geographic location to identify region-specific cutoffs, while also considering background antibody levels to distinguish between healthy and infected patients.
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Zoonotic Ancylostomiasis: An Update of a Continually Neglected Zoonosis
Katharina Stracke, Aaron R. Jex and Rebecca J. TraubPages: 网际直通车http://doi.org/10.4269/ajtmh.20-0060More LessAbstract.Hookworm infections are classified as the most impactful of the human soil-transmitted helminth (STH) infections, causing a disease burden of ∼4 million disability-adjusted life years, with a global prevalence of 406–480 million infections. Until a decade ago, epidemiological surveys largely assumed Necator americanus and Ancylostoma duodenale as the relevant human hookworm species implicated as contributing to iron-deficiency anemia. This assumption was based on the indistinguishable morphology of the Ancylostoma spp. eggs in stool and the absence of awareness of a third zoonotic hookworm species, Ancylostoma ceylanicum. The expanded use of molecular diagnostic assays for differentiating hookworm species infections during STH surveys has now implicated A. ceylanicum, a predominant hookworm of dogs in Asia, as the second most common hookworm species infecting humans in Southeast Asia and the Pacific. Despite this, with the exception of sporadic case reports, there is a paucity of data available on the impact of this emerging zoonosis on human health at a population level. This situation also challenges the current paradigm, necessitating a One Health approach to hookworm control in populations in which this zoonosis is endemic. Here, we have summarized the available research studies and case reports on human A. ceylanicum infections in Southeast Asia and the Pacific after 2013 using a systematic review approach. We summarized eight research articles and five clinical case studies, highlighting the importance of future in-depth investigation of zoonotic A. ceylanicum infections using sensitive and cost-effective diagnostic tools.
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网际直通车
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Volume 103 (2023)
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Most Cited This Month
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Techniques for Hemagglutination and Hemagglutination-Inhibition with Arthropod-Borne Viruses
D. H. Clarke and J. Casals
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Identification of Single Specimens of the Anopheles Gambiae Complex by the Polymerase Chain Reaction
Julie A. Scott, William G. Brogdon and Frank H. Collins
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The Epidemiology of Dengue in the Americas Over the Last Three Decades: A Worrisome Reality
José Luis San Martín, Olivia Brathwaite, Betzana Zambrano, José Orlando Solórzano, Alain Bouckenooghe, Gustavo H. Dayan and María G. Guzmán
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Vivax Malaria: Neglected and Not Benign
Ric N. Price, Emiliana Tjitra, Carlos A. Guerra, Shunmay Yeung, Nicholas J. White and Nicholas M. Anstey
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Research on Dengue during World War II 1
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A Neurotropic Virus Isolated from the Blood of a Native of Uganda 1
K. C. Smithburn, 网际直通车, A. W. Burke and J. H. Paul
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A Review of Malaria Diagnostic Tools: Microscopy and Rapid Diagnostic Test (RDT)
Chansuda Wongsrichanalai, Mazie J. Barcus, Sinuon Muth, 网际直通车 and Walther H. Wernsdorfer
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Ethics and Best Practice Guidelines for Training Experiences in Global Health
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周刊 - chinacourt.org:2021-10-24 · 群众反映问题,开通民意网上直通 车。黑龙江高院还制定了《“院长信 箱”所涉案件、事项办理工作的实施 细则》,规范信箱留言的梳理、批 转、办理和答复等流程。目前,全省 三级法院192个法院网站都开通了 “院长信箱”,极大地方便了当事人反 映诉求。
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The economic burden of malaria
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